製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      DALLKTGVKGLTAVSNNAGVDNFGLGLLLRSKQIKRMVSSYVGENAEFER QYLS
    • 分子量
      32 kDa including tags
    • 領域
      75 to 28

特性

Our Abpromise guarantee covers the use of ab116857 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 mg/ml. This protein is best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • 3 oxoacid CoA transferase 1
    • 3-oxoacid CoA-transferase 1
    • EC 2.8.3.5
    • OTTHUMP00000120012
    • OTTHUMP00000221550
    • OXCT
    • Oxct1
    • SCOT
    • Scot S
    • Scot-S
    • SCOT1_HUMAN
    • Somatic type succinyl CoA:3 oxoacid CoA transferase
    • Somatic-type succinyl-CoA:3-oxoacid CoA-transferase
    • Succinyl CoA:3 ketoacid CoA transferase
    • Succinyl CoA:3 ketoacid coenzyme A transferase 1 mitochondrial
    • Succinyl CoA:3 oxoacid CoA transferase
    • Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
    see all
  • 機能
    Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  • 組織特異性
    Abundant in heart, followed in order by kidney, brain, and muscle, whereas in liver it is undetectable; also detectable in leukocytes and fibroblasts.
  • パスウェイ
    Ketone metabolism; succinyl-CoA degradation; acetoacetyl-CoA from succinyl-CoA: step 1/1.
  • 関連疾患
    Succinyl-CoA:3-oxoacid CoA transferase deficiency
  • 配列類似性
    Belongs to the 3-oxoacid CoA-transferase family.
  • 細胞内局在
    Mitochondrion matrix.
  • Information by UniProt

画像

  • 12.5% SDS-PAGE showing ab116857 at approximately 31.57kDa and stained with Coomassie Blue.

参考文献

ab116857 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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