製品の概要

  • 製品名
    Recombinant Human ORC1 protein
  • タンパク質長
    Protein fragment

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MAHYPTRLTTRKTYSWVGRPLLDRKLHYQTYREMCVKTEGCSTEIHIQIG QFVLIEGDDDENPYVAKLLELFEDDSDPPPKKRARVQWFVRFCEVPACKR HLLGRKPGAQ
    • 分子量
      38 kDa including tags
    • 領域
      1 to 110
    • タグ
      GST tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab112336 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    Western blot

    SDS-PAGE

  • 製品の状態
    Liquid
  • 備考
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione

関連情報

  • 別名
    • HSORC1
    • MmORC1
    • orc1
    • ORC1_HUMAN
    • ORC1L
    • Origin Recognition Complex 1
    • Origin recognition complex subunit 1
    • Origin recognition complex subunit 1 (yeast homolog) like
    • Origin recognition complex subunit 1 homolog
    • Origin recognition complex subunit 1 like
    • Origin recognition complex subunit 1 like (S. cerevisia
    • Origin recognition complex subunit 1 S. cerevisiae homolog like
    • Origin recognition complex, subunit 1 like (yeast)
    • PARC1
    • Replication control protein 1
    see all
  • 機能
    Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
  • 配列類似性
    Belongs to the ORC1 family.
    Contains 1 BAH domain.
  • 発生段階
    Expression is cell-cycle regulated, it starts to accumulate in mid-G1 phase, reaches a peak at the G1/S boundary, and decreases to a basal level in S phase (at protein level).
  • 細胞内局在
    Nucleus.
  • Information by UniProt

画像

  • ab112336 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

参考文献

ab112336 has not yet been referenced specifically in any publications.

レビューと Q&A

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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