Recombinant Human OGT / O-Linked N-Acetylglucosamine Transferase protein (ab91749)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human
    • 配列SQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWL GYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANM FPHLKKKAVIDFKSNGHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCP DGGDNADSSNTALNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNG LATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDP STLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFS PVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETL ASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWK QRISSPLFNTKQYTMELERLYLQMWEHYAAGNK
    • 領域606 to 1022

特性

Our Abpromise guarantee covers the use of ab91749 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 製品の状態Lyophilised
  • 備考Protein Identity confirmed by Mass Spectrometry (MS/MS) (acquired on initial reference batch).
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5

  • 再構成Reconstitute with 81 µl aqua dest.

関連情報

  • 別名
    • FLJ23071
    • GlcNAc transferase
    • HRNT1
    • MGC22921
    • O GlcNAc
    • O GlcNAc transferase p110 subunit
    • O GlcNAc transferase subunit p110
    • O linked N acetylglucosamine (GlcNAc) transferase
    • O linked N acetylglucosamine (GlcNAc) transferase (UDP N acetylglucosamine:polypeptide N acetylglucosaminyl transferase)
    • O linked N acetylglucosamine transferase 110 kDa subunit
    • O-GlcNAc transferase subunit p110
    • O-linked N-acetylglucosamine transferase 110 kDa subunit
    • ogt
    • OGT1_HUMAN
    • UDP N acetylglucosamine peptide N acetylglucosaminyltransferase 110 kDa subunit
    • UDP N acetylglucosamine peptide N acetylglucosaminyltransferase GlcNAc transferase
    • UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
    • UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase
    • Uridinediphospho N acetylglucosamine:polypeptide beta N acetylglucosaminyl transferase
    see all
  • 機能Addition of nucleotide-activated sugars directly onto the polypeptide through O-glycosidic linkage with the hydroxyl of serine or threonine. Mediates the O-glycosylation of MLL5 and HCFC1. Promotes proteolytic maturation of HCFC1.
  • 組織特異性Highly expressed in pancreas and to a lesser extent in skeletal muscle, heart, brain and placenta. Present in trace amounts in lung and liver.
  • パスウェイProtein modification; protein glycosylation.
  • 配列類似性Belongs to the O-GlcNAc transferase family.
    Contains 13 TPR repeats.
  • ドメインThe TPR repeat domain mediates recognition of protein substrates.
  • 翻訳後修飾Ubiquitinated, leading to its proteasomal degradation.
  • 細胞内局在Cytoplasm. Nucleus. Mostly in the nucleus.
  • Information by UniProt

Recombinant Human OGT / O-Linked N-Acetylglucosamine Transferase protein 画像

  • The image shows an electrophoretic assay performed using an Agilent 5100 ALP. In some images coloured control bands can be seen at 15 kDa (green) and/or 240 kDa (purple). The protein-specific band is blue.

Recombinant Human OGT / O-Linked N-Acetylglucosamine Transferase protein (ab91749) 使用論文

ab91749 has not yet been referenced specifically in any publications.

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