The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
備考Protein concentration is above or equal to 0.05 mg/ml. Best use within three months from the date of receipt of this protein.
Concentration information loading...
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
Immediate-early response protein NOT
Intermediate early receptor protein
NGFI B/nur77 beta type transcription factor homolog
nuclear receptor of T cells
nuclear receptor related 1
Nuclear receptor subfamily 4 group A member 2
Nur related protein 1 homolog
nur related protein-1, human homolog of
Orphan nuclear receptor NR4A2
Orphan nuclear receptor NURR1
T cell nuclear receptor NOT
T-cell nuclear receptor NOT
Transcriptionally inducible nuclear receptor
Transcriptionally inducible nuclear receptor related
Transcriptionally inducible nuclear receptor related 1
Transcriptionally-inducible nuclear receptor
機能Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons.
組織特異性Expressed in a number of cell lines of T-cell, B-cell and fibroblast origin. Strong expression in brain tissue.
配列類似性Belongs to the nuclear hormone receptor family. NR4 subfamily. Contains 1 nuclear receptor DNA-binding domain.
発生段階Rapidly and only very transiently expressed after cell activation, during the G0-G1 transition of the cell cycle.