Recombinant Human NUDT10 protein (ab125779)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MKCKPNQTRT YDPEGFKKRA ACLCFRSERE DEVLLVSSSR YPDRWIVPGG GMEPEEEPGG AAVREVYEEA GVKGKLGRLL GVFEQNQDPK HRTYVYVLTV TELLEDWEDS VSIGRKREWF KVEDAIKVLQ CHKPVHAEYL EKLKLGGSPT NGNSMAPSSP DSDPLEHHHH HH
    • 分子量
      20 kDa including tags
    • 領域
      1 to 164
    • タグ
      His tag C-Terminus
    • 配列の追加情報
      NUDT10 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 172 amino acids (1-164 a.a.) and having a molecular mass of 19.5kDa.

特性

Our Abpromise guarantee covers the use of ab125779 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度
    > 95 % SDS-PAGE.
    ab125779 was purified by proprietary chromatographic techniques and filter sterilized.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride

関連情報

  • 別名
    • 5'''-P1
    • APS 2
    • APS2
    • Diadenosine 5'
    • Diadenosine 5' 5''' P1 P6 hexaphosphate hydrolase 3 alpha
    • Diadenosine hexaphosphate hydrolase (AMP-forming)
    • Diphosphoinositol polyphosphate phosphohydrolase 3, alpha
    • Diphosphoinositol polyphosphate phosphohydrolase 3-alpha
    • Diphosphoinositol polyphosphate phosphohydrolase type 3 alpha
    • DIPP 3 alpha
    • DIPP 3a
    • DIPP-3-alpha
    • DIPP3 alpha
    • DIPP3-alpha
    • DIPP3a
    • hAps 2
    • hAps2
    • hDIPP3alpha
    • Nucleoside diphosphate linked moiety X motif 10
    • Nucleoside diphosphate-linked moiety X motif 10
    • NUD10_HUMAN
    • Nudix (nucleoside diphosphate linked moiety X) type motif 10
    • Nudix motif 10
    • Nudix type motif 10
    • NUDT 10
    • NUDT10
    • P6-hexaphosphate hydrolase 3-alpha
    see all
  • 機能
    Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
  • 組織特異性
    Mainly expressed in testis and, at lower level in brain. According to PubMed:12121577, it is widely expressed.
  • 配列類似性
    Belongs to the Nudix hydrolase family. DIPP subfamily.
    Contains 1 nudix hydrolase domain.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt

参考文献

ab125779 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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