Recombinant Human NTH1 protein (ab113607)

製品の概要

  • 製品名Recombinant Human NTH1 protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P78549
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMCSPQESGMTALSARMLTRSRSLGPGAGPR GCREEPGPLRRREAAAEARKSHSPVKRPRKAQRLRVAYEGSDSEKGEGAE PLKVPVWEPQDWQQQLVNIRAMRNKKDAPVDHLGTEHCYDSSAPPKVRRY QVLLSLMLSSQTKDQVTAGAMQRLRARGLTVDSILQTDDATLGKLIYPVG FWRSKVKYIKQTSAILQQHYGGDIPASVAELVALPGVGPKMAHLAMAVAW GTVSGIAVDTHVHRIANRLRWTKKATKSPEETRAALEEWLPRELWHEING LLVGFGQQTCLPVHPRCHACLNQALCPAAQGL
    • 分子量37 kDa including tags
    • 領域1 to 312
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab113607 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度> 80 % SDS-PAGE.
    ab113607 was purified using conventional chromatography.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 40% Glycerol, 0.88% Sodium chloride, 0.02% DTT

関連情報

  • 別名
    • Bifunctional DNA N glycoslyase/DNA (apurinic or apyrimidinic site) lyase
    • DNA glycoslyase/AP lyase
    • Endonuclease III like protein 1
    • Endonuclease III-like protein 1
    • hNTH1
    • NTH 1
    • NTH endonuclease III Like 1
    • nth endonuclease III like 1 (E. coli)
    • NTH1
    • NTHL 1
    • Nthl1
    • NTHL1_HUMAN
    • OCTS 3
    • OCTS3
    see all
  • 機能Has both an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity. Incises damaged DNA at cytosines, thymines and guanines. Acts on a damaged strand, 5' from the damaged site. Required for the repair of both oxidative DNA damage and spontaneous mutagenic lesions.
  • 組織特異性Widely expressed with highest levels in heart and lowest levels in lung and liver.
  • 配列類似性Belongs to the Nth/MutY family.
  • 発生段階Expression levels are regulated during the cell cycle with increased levels during early and mid S-phase.
  • 細胞内局在Nucleus.
  • Information by UniProt

Recombinant Human NTH1 protein 画像

  • 15% SDS-PAGE analysis of ab113607 (3µg)

Recombinant Human NTH1 protein (ab113607) 使用論文

ab113607 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your inquiry. I heard back from the lab that ab113607 is not denatured.  I hope this information helps.  Please contact us with any other questions.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"