製品の概要

  • 製品名
    Recombinant Human NT5M protein
  • タンパク質長
    Full length protein

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHHSSGLVPRGSHMGGRALRVLVDMDGVLADFEGGFLRKFRAR FPDQPFIALEDRRGFWVS EQYGRLRPGLSEKAISIWESKNFFFELEPL PGAVEAVKEMASLQNTDVFICTSPIKMFKYCPYEKYAWVEKYFGP DFL EQIVLTRDKTVVSADLLIDDRPDITGAEPTPSWEHVLFTACHNQHLQLQP PRRRLHSWADDWKAILDSKRPC
    • 分子量
      25 kDa including tags
    • 領域
      32 to 228
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab113140 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Functional Studies

    SDS-PAGE

  • 質量分析
    MALDI-TOF
  • 精製度
    > 95 % SDS-PAGE.
    ab113140 was purified using conventional chromatography.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride, 0.02% DTT

関連情報

  • 別名
    • 3''-nucleotidase
    • 5''
    • 5''(3'')-deoxyribonucleotidase
    • 5'(3')-deoxyribonucleotidase, mitochondrial
    • 5',3'-nucleotidase, mitochondrial
    • Deoxy-5''-nucleotidase 2
    • dNT-2
    • DNT2
    • mitochondrial
    • NT5M
    • NT5M_HUMAN
    see all
  • 機能
    Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP.
  • 組織特異性
    Highly expressed in heart, brain and skeletal muscle. Detected at very low levels in kidney and pancreas.
  • 配列類似性
    Belongs to the 5'(3')-deoxyribonucleotidase family.
  • 細胞内局在
    Mitochondrion.
  • Information by UniProt

画像

  • 15% SDS-PAGE analysis of ab113140 (3µg)

参考文献

ab113140 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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