Recombinant Human NSMase2 protein (ab112416)
Key features and details
- Expression system: Wheat germ
- Suitable for: SDS-PAGE, WB, ELISA
製品の詳細
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製品名
Recombinant Human NSMase2 protein -
生理活性
useful for Antibody Production and Protein Array -
発現系
Wheat germ -
アクセッション番号
-
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
予測される分子量
98 kDa including tags -
領域
1 to 655
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関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab112416 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
Western blot
ELISA
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製品の状態
Liquid -
備考
This product is useful for Antibody Production and Protein Array.
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
(Glutathione is reduced)
関連情報
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別名
- Cca1
- Confluent 3Y1 cell-associated protein 1
- Neutral sphingomyelinase 2
see all -
機能
Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization. -
組織特異性
Predominantly expressed in brain. -
配列類似性
Belongs to the neutral sphingomyelinase family. -
発生段階
Up-regulated during G0/G1 phases. -
細胞内局在
Golgi apparatus membrane. Cell membrane. May localize to detergent-resistant subdomains of Golgi membranes of hypothalamic neurosecretory neurons. According to PubMed:15051724, it localizes to plasma membrane in confluent contact-inhibited cells. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (1)
ab112416 は 1 報の論文で使用されています。
- Xia J et al. Shufeng Jiedu Capsule and its active ingredients induce apoptosis, inhibit migration and invasion, and enhances doxorubicin therapeutic efficacy in hepatocellular carcinoma. Biomed Pharmacother 99:921-930 (2018). PubMed: 29710492