Recombinant Human NR5A2 / LRH1 protein (ab81844)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% Immunogen affinity purified
- Suitable for: WB, GSA
製品の詳細
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製品名
Recombinant Human NR5A2 / LRH1 protein
NR5A2 / LRH1 タンパク質・ペプチド 製品一覧 -
精製度
> 95 % Immunogen affinity purified.
Purified LRH-1 protein is greater than 95% homogeneous and contains no detectable protease, DNase, and RNase activity. -
発現系
Escherichia coli -
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human
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特性
Our Abpromise guarantee covers the use of ab81844 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Western blot
Gel Supershift Assays
EMSA
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製品の状態
Liquid -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.9
Constituents: 0.75% Potassium chloride, 0.0154% DTT, 0.316% Tris HCl, 0.00584% EDTA, 20% Glycerol (glycerin, glycerine)
関連情報
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別名
- Alpha-1-fetoprotein transcription factor
- B1-binding factor
- B1F
see all -
機能
Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development. -
組織特異性
Abundantly expressed in pancreas, less in liver, very low levels in heart and lung. Expressed in the Hep-G2 cell line. Isoform 1 and isoform 2 seem to be present in fetal and adult liver and Hep-G2 cells. -
配列類似性
Belongs to the nuclear hormone receptor family. NR5 subfamily.
Contains 1 nuclear receptor DNA-binding domain. -
細胞内局在
Nucleus. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab81844 は 1 報の論文で使用されています。
- Hughes CHK et al. NR5A2 and potential regulatory miRNAs in the bovine CL during early pregnancy. Reproduction 161:173-182 (2021). PubMed: 33320828