The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
備考Protein concentration is above or equal to 0.05 µg/ul.
Best use within three months from the date of receipt of this protein.
Concentration information loading...
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
Homeobox protein NK-3 homolog A
Homeobox protein Nkx 3.1
Homeobox protein Nkx-3.1
Homeobox protein Nkx3.1
NK homeobox (Drosophila) family 3 A
NK homeobox family 3 A
NK homeobox, family 3, member A
NK3 homeobox 1
NK3 transcription factor homolog A
NK3 transcription factor related locus 1
Nkx3.1, mouse, homolog of
機能Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Play an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
組織特異性Highly expressed in the prostate and, at a lower level, in the testis.
配列類似性Belongs to the NK-3 homeobox family. Contains 1 homeobox DNA-binding domain.
翻訳後修飾Ubiquitinated by TOPORS; monoubiquitinated at several residues and also polyubiquitinated on single residues.