製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Saccharomyces cerevisiae
  • アミノ酸配列
    • 生物種Human
    • 配列MTSFRLALIQLQISSIKSDNVTRACSFIREAATQGAKIVSLPECFNSPYG AKYFPEYA EKIPGESTQKLSEVAKECSIYLIGGSIPEEDAGKLYNTCA VFGPDGTLLAKYRKIHLF DIDVPGKITFQESKTLSPGDSFSTFDTPYC RVGLGICYDMRFAELAQIYAQRGCQLLV YPGAFNLTTGPAHWELLQRS RAVDNQVYVATASPARDDKASYVAWGHSTVVNPWGEVL AKAGTEEAIV YSDIDLKKLAEIRQQIPVFRQKRSDLYAVEMKKP

特性

Our Abpromise guarantee covers the use of ab88137 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 90 % SDS-PAGE.
    ab88137 was purified by affinity chromatography.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 30% Glycerol, 0.5% Triton-X-100, 50mM HEPES, 30mM Glutathione, 100mM Sodium chloride, 1mM DTT, pH 7.5

関連情報

  • 別名
    • CUA002
    • MGC111199
    • NIT 2
    • Nit protein 2
    • NIT2
    • NIT2_HUMAN
    • Nitrilase family member 2
    • Nitrilase homolog 2
    • Omega amidase NIT2
    • Omega-amidase NIT2
    see all
  • 機能Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle.
  • 組織特異性Detected in fetal brain (at protein level). Ubiquitous. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, prostate, spleen, thymus, prostate, testis, ovary, small intestine and colon.
  • 配列類似性Belongs to the UPF0012 family.
    Contains 1 CN hydrolase domain.
  • 細胞内局在Cytoplasm.
  • Information by UniProt

Recombinant Human NIT2 protein (ab88137) 使用論文

ab88137 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"