Recombinant Human Nicotinic Acetylcholine Receptor epsilon protein (ab114817)

製品の概要

  • 製品名Recombinant Human Nicotinic Acetylcholine Receptor epsilon protein
  • タンパク質長Protein fragment

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号Q04844
    • 生物種Human
    • 配列KNEELRLYHHLFNNYDPGSRPVREPEDTVTISLKVTLTNLISLNEKEETL TTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSELVWLPEIVLENNIDGQF GVAYDANVLV
    • 分子量38 kDa including tags
    • 領域21 to 130

特性

Our Abpromise guarantee covers the use of ab114817 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • Acetylcholine receptor subunit epsilon
    • ACHE_HUMAN
    • AChR
    • AchR epsilon subunit
    • ACHRE
    • Cholinergic receptor, nicotinic, epsilon polypeptide
    • Chrne
    • CMS1D
    • CMS1E
    • CMS2A
    • FCCMS
    • SCCMS
    see all
  • 機能After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
  • 関連疾患The muscle AChR is the major target antigen in the autoimmune disease myasthenia gravis. Myasthenia gravis is characterized by sporadic muscular fatigability and weakness, occurring chiefly in muscles innervated by cranial nerves, and characteristically improved by cholinesterase-inhibiting drugs.
    Myasthenic syndrome, congenital, 4A, slow-channel
    Myasthenic syndrome, congenital, 4B, fast-channel
    Myasthenic syndrome, congenital, 4C, associated with acetylcholine receptor deficiency
  • 配列類似性Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Epsilon/CHRNE sub-subfamily.
  • 細胞内局在Cell junction, synapse, postsynaptic cell membrane. Cell membrane.
  • Information by UniProt

Recombinant Human Nicotinic Acetylcholine Receptor epsilon protein 画像

  • 12.5% SDS-PAGE Stained with Coomassie Blue

Recombinant Human Nicotinic Acetylcholine Receptor epsilon protein (ab114817) 使用論文

ab114817 has not yet been referenced specifically in any publications.

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