製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q9NX24
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMTKIKADPDGPEAQAEACSGERTYQELLVN QNPIAQPLASRRLTRKLYKCIKKAVKQKQIRRGVKEVQKFVNKGEKGIMV LAGDTLPIEVYCHLPVMCEDRNLPYVYIPSKTDLGAAAGSKRPTCVIMVK PHEEYQEAYDECLEEVQSLPLPL
    • 分子量19 kDa including tags
    • 領域1 to 153
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab102027 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度> 90 % SDS-PAGE.
    ab102027 was purified using conventional chromatography.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0

関連情報

  • 別名
    • DKCB2
    • FLJ20479
    • H/ACA ribonucleoprotein complex subunit 2
    • NHP2
    • NHP2 like protein
    • NHP2 ribonucleoprotein
    • NHP2 ribonucleoprotein homolog
    • NHP2 ribonucleoprotein homolog (yeast) 1
    • NHP2, S. cerevisiae, homolog of
    • NHP2_HUMAN
    • NHP2P
    • NOLA2
    • Nucleolar protein family A member 2
    • Nucleolar protein family A member 2 (H/ACA small nucleolar RNPs)
    • snoRNP protein NHP2
    see all
  • 機能Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
  • 組織特異性Expressed in brain, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine, spleen, testis and thymus. Also expressed at lower levels in the liver.
  • 関連疾患Dyskeratosis congenita, autosomal recessive, 2
  • 配列類似性Belongs to the ribosomal protein L7Ae family.
  • 発生段階Transcript peaks at G1/S transition.
  • 細胞内局在Nucleus > nucleolus. Nucleus > Cajal body. Also localized to Cajal bodies.
  • Information by UniProt

Recombinant Human NHP2 protein 画像

  • 15% SDS-PAGE analysis of ab102027 (3µg)

Recombinant Human NHP2 protein (ab102027) 使用論文

ab102027 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab102027.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"