製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P01138
    • 生物種Human
    • 分子量14 kDa
    • 領域1 to 119

特性

Our Abpromise guarantee covers the use of ab105059 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性The ED50 as determined by the ability to stimulate neurite growth in Chick E9 DRG cells is < 1.0 ng/ml.
  • アプリケーション

    SDS-PAGE

    HPLC

  • エンドトキシン・レベル< 0.100 Eu/µg
  • 精製度> 95 % SDS-PAGE.
    The protein is purified by proprietary chromatographic techniques. >97% by SDS-PAGE and HPLC analyses
  • 製品の状態Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at -80°C. Avoid freeze / thaw cycle. For long term storage it is recommended to add a carrier protein on reconstitution (0.1% HSA or BSA).

    Preservative: None

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. The solution can be diluted into other aqueous buffers and stored at –20°C for future use.

関連情報

  • 別名
    • Beta nerve growth factor
    • Beta NGF
    • Beta-nerve growth factor
    • Beta-NGF
    • HSAN5
    • MGC161426
    • MGC161428
    • Nerve growth factor
    • Nerve growth factor (beta polypeptide)
    • Nerve growth factor beta
    • Nerve growth factor beta polypeptide
    • Nerve growth factor beta subunit
    • NGF
    • NGF_HUMAN
    • NGFB
    • NID67
    see all
  • 機能Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).
  • 関連疾患Neuropathy, hereditary sensory and autonomic, 5
  • 配列類似性Belongs to the NGF-beta family.
  • 細胞内局在Secreted.
  • Information by UniProt

Recombinant human NGF protein (ab105059) 使用論文

ab105059 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab105059.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"