Recombinant human Neuritin protein (ab69755)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies
製品の詳細
-
製品名
Recombinant human Neuritin protein -
生理活性
Determined by a cell proliferation using rat C6 cells. The ED50 for this effect is 20.0-30.0 ng/mL.
-
精製度
> 98 % SDS-PAGE.
Purity is greater than 98% by SDS-PAGE and HPLC analyses. Endotoxin level is <0.100 ng/µg. -
エンドトキシン・レベル
< 1.000 Eu/µg -
発現系
Escherichia coli -
アクセッション番号
-
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
-
生物種
Human -
配列
M-AGKCDAVFK GFSDCLLKLG DSMANYPQGL DDKTNIKTVC TYWEDFHSCT VTALTDCQEG AKDMWDKLRK ESKNLNIQGS LFELCGSGN -
予測される分子量
19 kDa -
領域
28 to 115
-
関連製品
-
Related Products
特性
Our Abpromise guarantee covers the use of ab69755 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
アプリケーション
SDS-PAGE
Functional Studies
-
製品の状態
Lyophilized -
Concentration information loading...
前処理および保存
-
保存方法および安定性
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
-
再構成Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8oC for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20oC to -80oC.
関連情報
-
別名
- Neuritin
- Neuritin 1
- NRN
see all -
機能
Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells. -
配列類似性
Belongs to the neuritin family. -
細胞内局在
Cell membrane. Cell junction > synapse. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
-
Datasheet download
参考文献 (2)
ab69755 は 2 報の論文で使用されています。
- Gonzalez-Figueroa P et al. Follicular regulatory T cells produce neuritin to regulate B cells. Cell 184:1775-1789.e19 (2021). PubMed: 33711260
- Sato H et al. Thalamus-derived molecules promote survival and dendritic growth of developing cortical neurons. J Neurosci 32:15388-402 (2012). PubMed: 23115177