製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P18615
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMLVIPPGLSEEEEALQKKFNKLKKKKKALL ALKKQSSSSTTSQGGVKRSLSEQPVMDTATATEQAKQLVKSGAISAIKAE TKNSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADDDLQESSRRPQRK SLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSA SPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRER DRDRERDRDRDREGPFRRSDSFPERRAPRKGNTLYVYGEDMTPTLLRGAF SPFGNIIDLSMDPPRNCAFVTYEKMESADQAVAELNGTQVESVQLKVNIA RKQPMLDAATGKSVWGSLAVQNSPKGCHRDKRTQIVYSDDVYKENLVDGF
    • 分子量45 kDa including tags
    • 領域1 to 380
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab104637 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度> 85 % SDS-PAGE.
    ab104637 is purified using conventional chromatography techniques.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 2mM DTT, pH 8.0

関連情報

  • 別名
    • Major histocompatibility complex gene RD
    • Negative elongation factor E
    • Negative elongation factor polypeptide E
    • NELF e
    • NELF-E
    • Nelfe
    • NELFE_HUMAN
    • Nuclear protein
    • RD
    • RD protein
    • RD RNA binding protein
    • RDP
    • RNA-binding protein RD
    see all
  • 機能Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex.
  • 組織特異性Widely expressed. Expressed in heart, brain, lung, placenta, liver, skeletal muscle, kidney and pancreas.
  • 配列類似性Belongs to the RRM NELF-E family.
    Contains 1 RRM (RNA recognition motif) domain.
  • ドメインThe RRM domain interacts with RNA, and is essential for NELF complex function. It is however not required for the NELF complex formation.
  • 翻訳後修飾Sumoylated.
  • 細胞内局在Nucleus.
  • Information by UniProt

Recombinant Human NELFe protein 画像

  • 15% SDS-PAGE analysis of 3µg ab104637.
    Note: Real molecular weight on SDS-PAGE is shifted up compared to predicted molecular weight.

Recombinant Human NELFe protein (ab104637) 使用論文

ab104637 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"