Recombinant Human NDUFS2 protein (ab114810)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      SPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVS DGSSRPYRCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEVDR
    • 分子量
      37 kDa including tags
    • 領域
      364 to 463

特性

Our Abpromise guarantee covers the use of ab114810 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • CI 49
    • CI 49kD
    • CI-49kD
    • Complex 1, mitochondrial respiratory chain, 49 KD subunit
    • Complex I 49kD
    • Complex I 49kDa subunit
    • Complex I-49kD
    • mitochondrial
    • NADH dehydrogenase (ubiquinone) Fe S protein 2 49kDa
    • NADH dehydrogenase (ubiquinone) Fe S protein 2, 49kDa (NADH coenzyme Q reductase)
    • NADH dehydrogenase [ubiquinone] iron sulfur protein 2, mitochondrial
    • NADH dehydrogenase [ubiquinone] iron-sulfur protein 2
    • NADH ubiquinone oxidoreductase 49 kDa subunit
    • NADH ubiquinone oxidoreductase NDUFS2 subunit
    • NADH-ubiquinone oxidoreductase 49 kDa subunit
    • NADH:ubiquinone oxidoreductase core subunit S2
    • Ndufs2
    • NDUS2_HUMAN
    see all
  • 機能
    Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
  • 関連疾患
    Defects in NDUFS2 are a cause of mitochondrial complex I deficiency (MT-C1D) [MIM:252010]. A disorder of the mitochondrial respiratory chain that causes a wide range of clinical disorders, from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease.
  • 配列類似性
    Belongs to the complex I 49 kDa subunit family.
  • 細胞内局在
    Mitochondrion inner membrane.
  • Information by UniProt

画像

  • 12.5% SDS-PAGE Stained with Coomassie Blue

参考文献

ab114810 has not yet been referenced specifically in any publications.

レビューと Q&A

There are currently no Customer reviews or Questions for ab114810.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録