製品の概要

  • 製品名Recombinant Human NDST1 protein
  • タンパク質長Protein fragment

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号P52848
    • 生物種Human
    • 配列LYGWKRGLEPSADAPEPDCGDPPPVAPSRLLPLKPVQAATPSRTDPLVLV FVESLYSQLGQEVVAILESSRFKYRTEIAPGKGDMPTLTDKGRGRFALI
    • 分子量37 kDa including tags
    • 領域38 to 136

関連製品

特性

Our Abpromise guarantee covers the use of ab116875 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • [Heparan sulfate]-glucosamine N-sulfotransferase 1
    • Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1
    • Glucosaminyl N-deacetylase/N-sulfotransferase 1
    • Heparan sulfate N-deacetylase 1
    • Heparan sulfate N-sulfotransferase 1
    • HSNST 1
    • HSST
    • HSST1
    • N-heparan sulfate sulfotransferase 1
    • N-HSST 1
    • NDST-1
    • Ndst1
    • NDST1_HUMAN
    see all
  • 機能Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response.
  • 組織特異性Widely expressed. Expression is most abundant in heart, liver and pancreas.
  • パスウェイGlycan metabolism; heparan sulfate biosynthesis.
    Glycan metabolism; heparin biosynthesis.
  • 配列類似性Belongs to the sulfotransferase 1 family. NDST subfamily.
  • 細胞内局在Golgi apparatus membrane.
  • Information by UniProt

Recombinant Human NDST1 protein 画像

  • 12.5% SDS-PAGE of ab116875 at approximately 36.52kDa, stained with Coomassie Blue.

Recombinant Human NDST1 protein (ab116875) 使用論文

ab116875 has not yet been referenced specifically in any publications.

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