製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      EPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDE ENEEVSINSQGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPV
    • 分子量
      36 kDa including tags
    • 領域
      2 to 96

関連製品

特性

Our Abpromise guarantee covers the use of ab114377 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 µg/µl.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • 1A1 3B
    • 1A13B
    • B box protein
    • Cell migration-inducing gene 19 protein
    • KIAA0049
    • M17S2
    • Membrane component chromosome 17 surface marker 2
    • Membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125)
    • MIG 19
    • MIG19
    • Migration inducing protein 19
    • NBR 1
    • Nbr1
    • NBR1, autophagy cargo receptor
    • NBR1_HUMAN
    • Neighbor of BRCA1 gene 1
    • Neighbor of BRCA1 gene 1 protein
    • Next to BRCA1 gene 1 protein
    • Ovarian carcinoma antigen CA125
    • Protein 1A1-3B
    see all
  • 機能
    Acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets.
  • 配列類似性
    Contains 1 OPR domain.
    Contains 1 UBA domain.
    Contains 1 ZZ-type zinc finger.
  • ドメイン
    The OPR domain mediates interaction with SQSTM1.
  • 細胞内局在
    Cytoplasm. Cytoplasmic vesicle > autophagosome. Lysosome. Cytoplasm > myofibril > sarcomere > M line. In cardiac muscles localizes to the sarcomeric M line (By similarity). Is targeted to lysosomes for degradation.
  • Information by UniProt

画像

  • 12.5% SDS-PAGE with ab114377 at approximately 36.08kDa stained with Coomassie Blue.

参考文献

ab114377 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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