Recombinant Human Nardilysin protein (ab92081)

製品の概要

  • 製品名Recombinant Human Nardilysin protein
  • タンパク質長Protein fragment

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human
    • 配列LGYHVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIE NLTEEAFNTQ VTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAH EIEALKSFSKSDLVNWFKAHRG PGSKMLSVHVVGYGKYELEEDGTPSS EDSNSSCEVMQLTYLPTSPLLADCIIPITDIRAF TTTLNLLPYHK
    • 領域958 to 1148

特性

Our Abpromise guarantee covers the use of ab92081 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 製品の状態Lyophilised
  • 備考Protein Identity confirmed by Mass Spectrometry (MS/MS) (acquired on initial reference batch).
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5

  • 再構成Reconstitute with 92 µl aqua dest.

関連情報

  • 別名
    • EC 3.4.24.61
    • hNRD1
    • hNRD2
    • N arginine dibasic convertase
    • Nardilysin precursor
    • NRD C
    • NRD convertase
    • NRD1
    see all
  • 関連性A member of the metalloproteinase family M16, nardilysin is most similar to insulin degrading enzyme, and the bacterial peptidase pitrilysin. It cleaves peptide substrates on the N terminus of arginine residues in dibasic pairs. Nardilysin was first described as a processing enzyme of somatostatin 1-28, which is cleaved at the Arg-Lys paired amino acid location. Nardilysin was named N arginine dibasic convertase (NRD convertase) to reflect this cleavage, although it was later shown that the activity was due to aminopeptidase B acting as a heterodimer with nardilysin. In addition to somatostatin 1-28, nardilysin cleaves dynorphin A and a-neoendorphin. Nardilysin was first detected in the brain and testis, and later in the heart, skeletal muscle, and in lesser amounts in most tissues and cell lines.

Recombinant Human Nardilysin protein 画像

  • The image shows an electrophoretic assay performed using an Agilent 5100 ALP. In some images coloured control bands can be seen at 15 kDa (green) and/or 240 kDa (purple). The protein-specific band is blue.

Recombinant Human Nardilysin protein (ab92081) 使用論文

ab92081 has not yet been referenced specifically in any publications.

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