製品の概要

  • 製品名Recombinant Human NAGLU protein
  • タンパク質長Protein fragment

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号P54802
    • 生物種Human
    • 配列YQLTLWGPEGNILDYANKQLAGLVANYYTPRWRLFLEALVDSVAQGIPFQ QHQFDKNVFQLEQAFVLSKQRYPSQPRGDTVDLAKKIFLKYYPGWVAGS
    • 分子量37 kDa including tags
    • 領域644 to 742

特性

Our Abpromise guarantee covers the use of ab114822 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • Alpha N acetylglucosaminidase
    • alpha N acetylglucosaminidase, lysosomal
    • Alpha-N-acetylglucosaminidase 77 kDa form
    • ANAG
    • ANAG_HUMAN
    • MPS IIIB
    • MPS3B
    • N acetyl alpha glucosaminidase
    • N acetylglucosaminidase, alpha
    • N-acetyl-alpha-glucosaminidase
    • NAG
    • NAGLU
    • UFHSD
    • UFHSD 1
    • UFHSD1
    see all
  • 機能Involved in the degradation of heparan sulfate.
  • 組織特異性Liver, ovary, peripheral blood leukocytes, testis, prostate, spleen, colon, lung, placenta and kidney.
  • 関連疾患Defects in NAGLU are the cause of mucopolysaccharidosis type 3B (MPS3B) [MIM:252920]; also known as Sanfilippo syndrome B. MPS3B is a form of mucopolysaccharidosis type 3, an autosomal recessive lysosomal storage disease due to impaired degradation of heparan sulfate. MPS3 is characterized by severe central nervous system degeneration, but only mild somatic disease. Onset of clinical features usually occurs between 2 and 6 years; severe neurologic degeneration occurs in most patients between 6 and 10 years of age, and death occurs typically during the second or third decade of life.
  • 細胞内局在Lysosome.
  • Information by UniProt

Recombinant Human NAGLU protein 画像

  • 12.5% SDS-PAGE Stained with Coomassie Blue

Recombinant Human NAGLU protein (ab114822) 使用論文

ab114822 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"