製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      DGHLQAVGSCPRLTPPPADLPLALPAHGLWSRHILQQTLMDEGLRLARLV SHDRVGRLSPCVPAKPPLAEFEEGLLDRCPAPGPHPALVEGRRSSVKVEA EASRQ
    • 分子量
      37 kDa including tags
    • 領域
      421 to 525

関連製品

特性

Our Abpromise guarantee covers the use of ab116846 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • EGR 1 binding protein 2
    • EGR-1-binding protein 2
    • EGR1 binding protein 2
    • MADER
    • Melanoma associated delayed early response protein
    • Melanoma-associated delayed early response protein
    • MGC75085
    • Nab 2
    • nab2
    • NAB2_HUMAN
    • NGFI A binding protein 2
    • NGFI A binding protein 2 (EGR1 binding protein 2)
    • NGFI-A-binding protein 2
    • Protein MADER
    see all
  • 機能
    Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability.
  • 組織特異性
    Widely expressed at low levels. Highly expressed in melanoma cell lines.
  • 配列類似性
    Belongs to the NAB family.
  • ドメイン
    The NAB conserved domain 1 (NCD1) interacts with EGR1 inhibitory domain and mediates multimerization.
    The NAB conserved domain 2 (NCD2) is necessary for transcriptional repression.
  • 細胞内局在
    Nucleus. Isoform 2 is not localized to the nucleus.
  • Information by UniProt

画像

  • 12.5% SDS-PAGE stained with Coomassie Blue showing ab116846 at approximately 37.18 kDa.

参考文献

ab116846 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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