製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号P04198
    • 生物種Human
    • 配列MPSCSTSTMPGMICKNPDLEFDSLQPCFYPDEDDFYFGGPDSTPPGEDIW KKFELLPTPPLSPSRGFAEHSSEPPSWVTEMLLENELWGSPAEEDAFGLG
    • 分子量37 kDa including tags
    • 領域1 to 100
    • タグGST tag N-Terminus

関連製品

特性

Our Abpromise guarantee covers the use of ab112325 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    ELISA

    Western blot

  • 製品の状態Liquid
  • 備考Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione

関連情報

  • 別名
    • bHLHe37
    • Class E basic helix-loop-helix protein 37
    • MODED
    • mycn
    • MYCN_HUMAN
    • N myc
    • N myc proto oncogene protein
    • N-myc proto-oncogene protein
    • Neuroblastoma derived v myc avian myelocytomatosis viral related oncogene
    • Neuroblastoma MYC oncogene
    • NMYC
    • NMYC proto oncogene protein
    • ODED
    • Oncogene NMYC
    • pp65/67
    • v myc avian myelocytomatosis viral related oncogene neuroblastoma derived
    • v myc myelocytomatosis viral related oncogene neuroblastoma derived
    see all
  • 機能May function as a transcription factor.
  • 関連疾患Note=Amplification of the N-MYC gene is associated with a variety of human tumors, most frequently neuroblastoma, where the level of amplification appears to increase as the tumor progresses.
    Defects in MYCN are the cause of microcephaly-oculo-digito-esophageal-duodenal syndrome (MODED) [MIM:164280]; also known as oculodigitoesophagoduodenal syndrome (ODED). Microcephaly-oculo-digito-esophageal-duodenal syndrome is characterized by variable combinations of esophageal and duodenal atresias, microcephaly, learning disability and limb malformations. Cardiac and renal malformations, vertebral anomalies, and deafness have also been described.
    Defects in MYCN are the cause of microcephaly and digital abnormalities with normal intelligence (MCPHDANI) [MIM:602585].
  • 配列類似性Contains 1 basic helix-loop-helix (bHLH) domain.
  • 発生段階Expressed during fetal development.
  • 細胞内局在Nucleus.
  • Information by UniProt

Recombinant Human n-Myc protein 画像

  • ab112325 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

Recombinant Human n-Myc protein (ab112325) 使用論文

ab112325 has not yet been referenced specifically in any publications.

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