Recombinant Human Myosin Light Chain 2 protein (ab117178)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P10916
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMAPKKAKKRAGGANSNVFSMFEQTQIQEFK EAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMIKEAPGPINFT VFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVREMLTTQAERF SKEEVDQMFAAFPPDVTGNLDYKNLVHIITHGEEKD
    • 分子量21 kDa including tags
    • 領域1 to 166
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab117178 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 95 % SDS-PAGE.
    ab117178 is purified by proprietary chromatographic techniques.
  • 製品の状態Liquid
  • 備考ab117178 although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Please see notes section.

    pH: 8.00
    Constituents: 0.24% Tris, 20% Glycerol, 0.05% Calcium chloride

関連情報

  • 別名
    • Cardiac myosin light chain-2
    • Cardiac ventricular myosin light chain 2
    • CMH10
    • MLC 2v
    • MLC-2
    • MLC-2v
    • MLC2
    • MLRV_HUMAN
    • MYL 2
    • MYL2
    • Myosin light chain 2 regulatory cardiac slow
    • Myosin light polypeptide 2 regulatory cardiac slow
    • Myosin regulatory light chain 2
    • Myosin regulatory light chain 2 ventricular/cardiac muscle isoform
    • Regulatory light chain of myosin
    • RLC of myosin
    • Slow cardiac myosin regulatory light chain 2
    • ventricular/cardiac muscle isoform
    see all
  • 関連疾患Defects in MYL2 are the cause of cardiomyopathy familial hypertrophic type 10 (CMH10) [MIM:608758]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.
    Defects in MYL2 are the cause of cardiomyopathy familial hypertrophic with mid-left ventricular chamber type 2 (MVC2) [MIM:608758]. MVC2 is a very rare variant of familial hypertrophic cardiomyopathy, characterized by mid-left ventricular chamber thickening.
  • 配列類似性Contains 3 EF-hand domains.
  • 翻訳後修飾N-terminus is methylated by METTL11A/NTM1.
  • Information by UniProt

Recombinant Human Myosin Light Chain 2 protein (ab117178) 使用論文

ab117178 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"