製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q00059
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMSSVLASCPKKPVSSYLRFSKEQLPIFKAQ NPDAKTTELIRRIAQRWRELPDSKKKIYQDAYRAEWQVYKEEISRFKEQL TPSQIMSLEKEIMDKHLKRKAMTKKKELTLLGKPKRPRSAYNVYVAERFQ EAKGDSPQEKLKTVKENWKNLSDSEKELYIQHAKEDETRYHNEMKSWEEQ MIEVGRKDLLRRTIKKQRKYGAEEC
    • 分子量27 kDa including tags
    • 領域43 to 246
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab103784 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度> 85 % SDS-PAGE.
    ab103784 was purified by using anion-exchange chromatography (DEAE sepharose resin) and gel-filtration chromatography (Sephacryl S-200) with 20mM Tris pH 7.5, 2mM EDTA.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 0.2M Sodium chloride, 5mM DTT, 20mM Tris HCl, pH 8.0

関連情報

  • 別名
    • anscription factor 6-like 1
    • Mitochondrial transcription factor 1
    • mitochondrial transcription factor A
    • MtTF1
    • mtTFA
    • TCF 6
    • TCF-6
    • TCF6
    • TCF6L1
    • TCF6L2
    • TCF6L3
    • TFAM
    • TFAM_HUMAN
    • Transcription factor 6
    • Transcription factor 6 like 2
    • Transcription factor 6 like 2 (mitochondrial transcription factor)
    • Transcription factor 6-like 2
    • transcription factor 6-like 3
    • Transcription factor A, mitochondrial
    • Transcription factor A, mitochondrial precursor
    see all
  • 機能Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind and bend DNA. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. target DNA. Interacts with TFB1M and TFB2M.
  • 配列類似性Contains 2 HMG box DNA-binding domains.
  • 細胞内局在Mitochondrion.
  • Information by UniProt

Recombinant Human mtTFA protein 画像

  • 15% SDS-PAGE analysis of 3µg ab103784.

Recombinant Human mtTFA protein (ab103784) 使用論文

ab103784 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"