製品の概要

  • 製品名
    Recombinant Human MRP2 protein
  • タンパク質長
    Protein fragment

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      LKGYKRPLTLEDVWEVDEEMKTKTLVSKFETHMKRELQKARRALQRRQEK SSQQNSGARLPGLNKNQSQSQDALVLEDVEKKKKKSGTKKDVPKSWLMKA
    • 分子量
      37 kDa including tags
    • 領域
      214 to 313
    • タグ
      GST tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab112272 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性
    useful for Antibody Production and Protein Array
  • アプリケーション

    ELISA

    Western blot

    SDS-PAGE

  • 製品の状態
    Liquid
  • 備考
    Best use within three months from the date of receipt of this protein.useful for Antibody Production and Protein Array
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione
    Note: Glutathione is reduced

関連情報

  • 別名
    • ABC30
    • abcC2
    • ATP binding cassette sub family C (CFTR/MRP) member 2
    • ATP binding cassette subfamily C member 2
    • ATP-binding cassette sub-family C member 2
    • Canalicular multidrug resistance protein
    • Canalicular multispecific organic anion transporter 1
    • CMOAT
    • CMOAT1
    • cMRP
    • DJS
    • KIAA1010
    • MRP 2
    • MRP2_HUMAN
    • Multidrug resistance associated protein 2
    • Multidrug resistance-associated protein 2
    see all
  • 機能
    Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter.
  • 組織特異性
    Found on the apical membrane of polarized cells in liver, kidney and intestine. The highest expression is found in liver.
  • 関連疾患
    Defects in ABCC2 are the cause of Dubin-Johnson syndrome (DJS) [MIM:237500]. DJS is an autosomal recessive disorder characterized by conjugated hyperbilirubinemia, an increase in the urinary excretion of coproporphyrin isomer I, deposition of melanin-like pigment in hepatocytes, and prolonged retention of sulfobromophthalein, but otherwise normal liver function.
  • 配列類似性
    Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
    Contains 2 ABC transmembrane type-1 domains.
    Contains 2 ABC transporter domains.
  • 細胞内局在
    Membrane.
  • Information by UniProt

Recombinant Human MRP2 protein 画像

  • 12.5% SDS-PAGE Stained with Coomassie Blue

Recombinant Human MRP2 protein (ab112272) 使用論文

ab112272 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab112272.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録