製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P19105
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMGSHMSSKRTKTKTKKRPQRATSNVFAMFD QSQIQEFKEAFNMIDQNR DGFIDKEDLHDMLASLGKNPTDEYLDAMMN EAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQE DYL RELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD
    • 分子量22 kDa including tags
    • 領域1 to 171
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab113139 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Functional Studies

  • 質量分析
    MALDI-TOF
  • 精製度> 90 % SDS-PAGE.
    ab113139 was purified using conventional chromatography.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 20% Glycerol, 0.02% DTT

関連情報

  • 別名
    • ML12A_HUMAN
    • MLC 2B
    • MLC-2B
    • MLCB
    • MYL12A
    • Myosin regulatory light chain 12A
    • Myosin regulatory light chain 2
    • Myosin regulatory light chain 2, nonsarcomeric
    • Myosin regulatory light chain MRCL3
    • Myosin regulatory light chain MRLC3
    • Myosin RLC
    • Myosin, light polypeptide, regulatory, non sarcomeric (20kD)
    • nonsarcomeric
    • RLC
    see all
  • 機能Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion.
  • 配列類似性Contains 3 EF-hand domains.
  • 翻訳後修飾Phosphorylation increases the actin-activated myosin ATPase activity and thereby regulates the contractile activity. It is required to generate the driving force in the migration of the cells but not necessary for localization of myosin-2 at the leading edge.
  • Information by UniProt

Recombinant Human MRCL3 protein 画像

  • 15% SDS-PAGE analysis of ab113139 (3µg)

Recombinant Human MRCL3 protein (ab113139) 使用論文

ab113139 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"