製品の概要

  • 製品名Recombinant Human MID1 protein
  • タンパク質長Protein fragment

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号O15344
    • 生物種Human
    • 配列PNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLKTNSQPFKLDP KSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGR
    • 分子量37 kDa including tags
    • 領域441 to 540

関連製品

特性

Our Abpromise guarantee covers the use of ab114762 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 µg/ul.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • BBBG 1
    • BBBG1
    • E3 ubiquitin-protein ligase Midline-1
    • Finger on X and Y mouse homolog of
    • FXY
    • GBBB 1
    • GBBB1
    • MID 1
    • Mid1
    • Midin
    • Midline 1
    • Midline 1 (Opitz/BBB syndrome)
    • Midline 1 ring finger
    • Midline 1 RING finger protein
    • Midline-1
    • Midline1
    • OGS 1
    • OGS1
    • OS
    • OSX
    • Putative transcription factor XPRF
    • RING finger protein 59
    • RING finger protein Midline-1
    • RNF 59
    • RNF59
    • TRI18
    • TRI18_HUMAN
    • TRIM 18
    • TRIM18
    • Tripartite motif containing protein 18
    • Tripartite motif protein TRIM18
    • Tripartite motif-containing protein 18
    • XPRF
    • zinc finger on X and Y, mouse, homolog of
    • Zinc finger X and Y
    • ZNFXY
    see all
  • 機能May have E3 ubiquitin ligase activity which targets the catalytic subunit of protein phosphatase 2 for degradation.
  • 組織特異性In the fetus, highest expression found in kidney, followed by brain and lung. Expressed at low levels in fetal liver. In the adult, most abundant in heart, placenta and brain.
  • 関連疾患Defects in MID1 are the cause of Opitz syndrome type I (OS-I) [MIM:300000]. OS-I is an X-linked recessive disorder characterized by hypertelorism, genital-urinary defects such as hypospadias in males and splayed labia in females, lip-palate-laryngotracheal clefts, imperforate anus, developmental delay and congenital heart defects. OS-I mutations produce proteins with a decreased affinity for microtubules.
  • 配列類似性Belongs to the TRIM/RBCC family.
    Contains 2 B box-type zinc fingers.
    Contains 1 B30.2/SPRY domain.
    Contains 1 COS domain.
    Contains 1 fibronectin type-III domain.
    Contains 1 RING-type zinc finger.
  • 翻訳後修飾Phosphorylated on serine and threonine residues.
  • 細胞内局在Cytoplasm. Cytoplasm > cytoskeleton. Cytoplasm > cytoskeleton > spindle. Microtubule-associated. It is associated with microtubules throughout the cell cycle, co-localizing with cytoplasmic fibers in interphase and with the mitotic spindle and midbodies during mitosis and cytokinesis.
  • Information by UniProt

Recombinant Human MID1 protein 画像

  • 12.5% SDS-PAGE Stained with Coomassie Blue showing ab114762 at approximately 36.63kDa.

Recombinant Human MID1 protein (ab114762) 使用論文

ab114762 has not yet been referenced specifically in any publications.

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