由来 Escherichia coli
配列 MGSSHHHHHH SSGLVPRGSH MDKDCEMKRT TLDSPLGKLE LSGCEQGLHE IKLLGKGTSA ADAVEVPAPA AVLGGPEPLM QCTAWLNAYF HQPEAIEEFP VPAFHHPVFQ QESFTRQVLW KLLKVVKFGE VISYQQLAAL AGNPKAARAV GGAMRGNPVP ILIPCHRVVC SSGAVGNYSG GLAVKEWLLA HEGHRLGKPG LGGSSGLAGA WLKGAGATSG SPPAGRN 特性
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
精製度 > 95
% SDS-PAGE. ab79251 is purified using conventional chromatography techniques.
Endotoxin Level:< 1.0 EU per 1 µg of protein (determined by LAL method)
Concentration information loading... 前処理および保存
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 7.5
6 O methylguanine DNA methyltransferase
機能 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
配列類似性 Belongs to the MGMT family.
Information by UniProt
Recombinant Human MGMT protein (ab79251) 使用論文
has not yet been referenced specifically in any publications.
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