Recombinant Human MESDC2 protein (ab104671)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q14696
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMAEGSPGTPDESTPPPRKKKKDIRDYNDAD MARLLEQWEKDDDIEEGDLPEHKRPSAPVDFSKIDPSKPESILKMTKKGK TLMMFVTVSGSPTEKETEEITSLWQGSLFNANYDVQRFIVGSDRAIFMLR DGSYAWEIKDFLVGQDRCADVTLEGQVYPGKGGGSKEKNKTKQDKGKKKK EGDLKSRSSKEENRAGNKREDL
    • 分子量25 kDa including tags
    • 領域34 to 234
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab104671 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度> 90 % SDS-PAGE.
    ab104671 is purified by using anion-exchange chromatography (DEAE sepharose resin) and gel-filtration chromatography (Sephacryl S-200) with 20mM Tris pH 7.5, 2mM EDTA.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0

関連情報

  • 別名
    • BOCA
    • KIAA0081
    • LDLR chaperone MESD
    • MESD
    • MESD_HUMAN
    • MESDC 2
    • mesdc2
    • Mesoderm development candidate 2
    • Mesoderm development protein
    • Renal carcinoma antigen NY REN 61
    • Renal carcinoma antigen NY-REN-61
    see all
  • 機能Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction.
  • 配列類似性Belongs to the MESD family.
  • ドメインThe chaperone domain provides a folding template for proper folding of the beta-propeller (BP) domains of LRP5/6.
    The escort domain ensures LRP5/6 safe-trafficking from the ER to the Golgi by preventing premature ligand-binding.
  • 細胞内局在Endoplasmic reticulum.
  • Information by UniProt

Recombinant Human MESDC2 protein 画像

  • 15% SDS-PAGE showing ab104671 at approximately 24.9kDa (3µg).
    Note: Real molecular weight on SDS-PAGE is shifted up compared to predicted molecular weight.

Recombinant Human MESDC2 protein (ab104671) 使用論文

ab104671 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab104671.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"