Recombinant human Melanoma Inhibitory Activity protein (ab73232)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      M-GPMPKLADRKLCADQECSSHPISMAVALQDYMAPDCRFLTIHRGQVV YVFSLKGRGRFLWGGSVQGDYYGDLAARLGYFPSSIVREDQTLKVDVKT DKWDFYCQ.
    • 領域
      25 to 131

特性

Our Abpromise guarantee covers the use of ab73232 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性

    Calculated by the inhibiting effect on the invasion of Mel In Tumor cells (Bosserhoff et al.2003 Lab Invest. 83, 1583-94).

  • アプリケーション

    SDS-PAGE

    Functional Studies

  • 精製度
    > 95 % SDS-PAGE.
    This protein was purified by proprietary chromatographic techniques. Purity greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
  • 製品の状態
    Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20mM Potassium phosphate, 150mM Potassium chloride, pH 7.0

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成
    Reconstitute in sterile 18Mohm-cm water to at not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

関連情報

  • 別名
    • Cartilage derived retinoic acid sensitive protein
    • CD RAP
    • CDRAP
    • Melanoma derived growth regulatory protein precursor
    • Melanoma inhibitory activity protein
    • Melanoma-derived growth regulatory protein
    • Mia
    • MIA_HUMAN
    see all
  • 機能
    Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.
  • 組織特異性
    All malignant melanoma cell lines tested and infrequently in glioma cell lines.
  • 配列類似性
    Belongs to the MIA/OTOR family.
    Contains 1 SH3 domain.
  • 翻訳後修飾
    May possess two intramolecular disulfide bonds.
  • 細胞内局在
    Secreted.
  • Information by UniProt

Recombinant human Melanoma Inhibitory Activity protein (ab73232) 使用論文

ab73232 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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