Recombinant human Melanoma Inhibitory Activity protein (ab49847)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies
製品の詳細
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製品名
Recombinant human Melanoma Inhibitory Activity protein
Melanoma Inhibitory Activity タンパク質・ペプチド 製品一覧 -
生理活性
The ED50 was determined by the dose-dependant proliferation of the human A375 melanoma cell line. The expected ED50 for this effect is 4-6 μg/ml.
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精製度
> 95 % SDS-PAGE.
Greater than 98% by SDS-PAGE and HPLC analyses. -
発現系
Escherichia coli -
タンパク質長
Protein fragment -
Animal free
No -
由来
Recombinant -
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生物種
Human -
配列
MGPMPKLADR KLCADQECSH PISMAVALQD YMAPDCRFLT IHRGQVVYVF SKLKGRGRLF WGGSVQGDYY GDLAARLGYF PSSIVREDQT LKPGKVDVKT DKWDFYCQ
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特性
Our Abpromise guarantee covers the use of ab49847 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
Functional Studies
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製品の状態
Lyophilized -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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再構成Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4oC for 1 week or -20oC for future use.
関連情報
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別名
- Cartilage derived retinoic acid sensitive protein
- CD RAP
- CDRAP
see all -
機能
Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas. -
組織特異性
All malignant melanoma cell lines tested and infrequently in glioma cell lines. -
配列類似性
Belongs to the MIA/OTOR family.
Contains 1 SH3 domain. -
翻訳後修飾
May possess two intramolecular disulfide bonds. -
細胞内局在
Secreted. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab49847 は論文での使用が確認できていません。