製品の概要

  • 製品名Recombinant Human MAGEA3 protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P43357
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMGSMPLEQRSQHCKPEEGLEARGEALGLVG AQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNY PLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAR EPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYI FATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSV LEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRA LVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE
    • 分子量37 kDa including tags
    • 領域1 to 314
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab99958 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度> 90 % SDS-PAGE.
    ab99958 is purified using conventional chromatography techniques.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 100mM Sodium chloride, 1mM DTT, pH 8.0

関連情報

  • 別名
    • Antigen MZ2 D
    • Antigen MZ2-D
    • Cancer/testis antigen 1.3
    • Cancer/testis antigen family 1 member 3
    • CT1.3
    • HIP8
    • HYPD
    • MAGA3_HUMAN
    • MAGE 3 antigen
    • MAGE-3 antigen
    • MAGE3
    • MAGEA3
    • MAGEA6
    • Melanoma antigen family A 3
    • Melanoma associated antigen 3
    • Melanoma-associated antigen 3
    • MGC1461
    see all
  • 機能Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
  • 組織特異性Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta. Never expressed in kidney tumors, Leukemias and lymphomas.
  • 配列類似性Contains 1 MAGE domain.
  • Information by UniProt

Recombinant Human MAGEA3 protein 画像

  • 15% SDS-PAGE showing ab99958 (3µg).

Recombinant Human MAGEA3 protein (ab99958) 使用論文

ab99958 has not yet been referenced specifically in any publications.

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