製品の概要

  • 製品名Recombinant human MAGE 1 protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human
    • 分子量60 kDa including tags

特性

Our Abpromise guarantee covers the use of ab75539 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性MAGE 1 antibody reactive.
  • アプリケーション

    Western blot

    ELISA

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • Antigen MZ2 E
    • Antigen MZ2-E
    • Cancer/testis antigen 1.1
    • cancer/testis antigen family 1, member 1
    • CT1.1
    • MAGA1_HUMAN
    • MAGE 1 antigen
    • MAGE-1 antigen
    • MAGE1
    • MAGE1A
    • MAGEA1
    • Melanoma antigen 1
    • Melanoma antigen family A 1
    • Melanoma antigen family A 1 (directs expression of antigen MZ2 E)
    • Melanoma antigen MAGE 1
    • Melanoma associated antigen 1
    • Melanoma associated antigen MZ2 E
    • Melanoma-associated antigen 1
    • MGC9326
    see all
  • 機能May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
  • 組織特異性Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Never expressed in kidney tumors, leukemias and lymphomas.
  • 配列類似性Contains 1 MAGE domain.
  • 細胞内局在Cytoplasm. Nucleus.
  • Information by UniProt

Recombinant human MAGE 1 protein (ab75539) 使用論文

ab75539 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"