Recombinant Human MAD2L1 binding protein (ab123183)

製品の概要

  • 製品名Recombinant Human MAD2L1 binding protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q15013
    • 生物種Human
    • 配列MGSSHHHHHH SSGLVPRGSH MGSHMAAPEA EVLSSAAVPD LEWYEKSEET HASQIELLET SSTQEPLNAS EAFCPRDCMV PVVFPGPVSQ EGCCQFTCEL LKHIMYQRQQ LPLPYEQLKH FYRKPSPQAE EMLKKKPRAT TEVSSRKCQQ ALAELESVLS HLEDFFARTL VPRVLILLGG NALSPKEFYE LDLSLLAPYS VDQSLSTAAC LRRLFRAIFM ADAFSELQAP PLMGTVVMAQ GHRNCGEDWF RPKLNYRVPS RGHKLTVTLS CGRPSIRTTA WEDYIWFQAP VTFKGFRE
    • 分子量34 kDa including tags
    • 領域1 to 274
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab123183 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度> 90 % SDS-PAGE.
    ab123183 was purified using conventional chromatography techniques.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 10% Glycerol, 0.58% Sodium chloride

関連情報

  • 別名
    • Caught by MAD2 protein
    • CMT2
    • dJ261G23.1
    • KIAA0110
    • MAD2L1 binding protein
    • MAD2L1 binding protein isoform 2
    • MAD2L1-binding protein
    • Mad2l1bp
    • MD2BP_HUMAN
    • MGC11282
    • OTTHUMP00000016496
    • RP1 261G23.6
    see all
  • 機能May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.
  • 配列類似性Belongs to the MAD2L1BP family.
  • 発生段階During the cell cycle, levels increase and then remain constant until late mitosis after which they drop.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Nucleus. Cytoplasm > cytoskeleton > spindle. During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle.
  • Information by UniProt

Recombinant Human MAD2L1 binding protein 画像

  • 15% SDS-PAGE showing ab123183 (3µg). (Molecular size on SDS-PAGE will appear higher than predicted)

Recombinant Human MAD2L1 binding protein (ab123183) 使用論文

ab123183 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab123183.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"