Recombinant Human MAD2L1 binding protein (ab123183)

製品の概要

  • 製品名
    Recombinant Human MAD2L1 binding protein
  • タンパク質長
    Full length protein

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHH SSGLVPRGSH MGSHMAAPEA EVLSSAAVPD LEWYEKSEET HASQIELLET SSTQEPLNAS EAFCPRDCMV PVVFPGPVSQ EGCCQFTCEL LKHIMYQRQQ LPLPYEQLKH FYRKPSPQAE EMLKKKPRAT TEVSSRKCQQ ALAELESVLS HLEDFFARTL VPRVLILLGG NALSPKEFYE LDLSLLAPYS VDQSLSTAAC LRRLFRAIFM ADAFSELQAP PLMGTVVMAQ GHRNCGEDWF RPKLNYRVPS RGHKLTVTLS CGRPSIRTTA WEDYIWFQAP VTFKGFRE
    • 分子量
      34 kDa including tags
    • 領域
      1 to 274
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab123183 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度
    > 90 % SDS-PAGE.
    ab123183 was purified using conventional chromatography techniques.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 10% Glycerol, 0.58% Sodium chloride

関連情報

  • 別名
    • Caught by MAD2 protein
    • CMT2
    • dJ261G23.1
    • KIAA0110
    • MAD2L1 binding protein
    • MAD2L1 binding protein isoform 2
    • MAD2L1-binding protein
    • Mad2l1bp
    • MD2BP_HUMAN
    • MGC11282
    • OTTHUMP00000016496
    • RP1 261G23.6
    see all
  • 機能
    May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.
  • 配列類似性
    Belongs to the MAD2L1BP family.
  • 発生段階
    During the cell cycle, levels increase and then remain constant until late mitosis after which they drop.
  • 翻訳後修飾
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在
    Nucleus. Cytoplasm > cytoskeleton > spindle. During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle.
  • Information by UniProt

画像

  • 15% SDS-PAGE showing ab123183 (3µg). (Molecular size on SDS-PAGE will appear higher than predicted)

参考文献

ab123183 has not yet been referenced specifically in any publications.

レビューと Q&A

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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