Recombinant human Macrophage Inflammatory Protein 3 alpha (ab125762)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P78556
    • 生物種Human
    • 分子量8 kDa
    • 領域27 to 96

特性

Our Abpromise guarantee covers the use of ab125762 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性Determined by its ability to chemoattract Human T cells using a concentration range of 7-70 ng/ml.
  • アプリケーション

    SDS-PAGE

    HPLC

    Functional Studies

  • 精製度> 97 % SDS-PAGE.
    >97% by SDS-PAGE and HPLC analyses
  • 製品の状態Lyophilised
  • 備考Reconstituted ab125762 should be stored in working aliquots at -20°C. Avoid freeze/thaw cycles. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.Determined by its ability to chemoattract Human T cells using a concentration range of 7-70 ng/ml. Determined by its ability to chemoattract Human T cells using a concentration range of 7-70 ng/ml.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at -20°C. Store under Desiccating conditions.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers.

関連情報

  • 別名
    • Beta-chemokine exodus-1
    • C C motif chemokine ligand 20
    • C-C motif chemokine 20
    • CC chemokine LARC
    • Ccl20
    • CCL20(2-70)
    • CCL20_HUMAN
    • Chemokine (C C motif) ligand 20
    • Chemokine CC motif ligand 20
    • CKb4
    • Exodus
    • Exodus 1
    • LARC
    • Liver and activation-regulated chemokine
    • Macrophage inflammatory protein 3 alpha
    • MIP 3 alpha
    • MIP 3A
    • MIP-3-alpha
    • MIP-3a
    • MIP3A
    • SCYA20
    • Small inducible cytokine A20
    • Small inducible cytokine subfamily A (Cys Cys) member 20
    • Small-inducible cytokine A20
    • ST38
    see all
  • 機能Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213.
  • 組織特異性Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels seen in thymus, prostate, testis, small intestine and colon.
  • 配列類似性Belongs to the intercrine beta (chemokine CC) family.
  • 翻訳後修飾C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
  • 細胞内局在Secreted.
  • Information by UniProt

Recombinant human Macrophage Inflammatory Protein 3 alpha (ab125762) 使用論文

ab125762 has not yet been referenced specifically in any publications.

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