Recombinant Human Lipoamide Dehydrogenase protein (ab93679)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • 生物種
      Human

特性

Our Abpromise guarantee covers the use of ab93679 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Western blot

  • 精製度
    > 95 % SDS-PAGE.
    ab93679 is purified using conventional chromatography techniques.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0

関連情報

  • 別名
    • Dehydrogenase complex, E3 component
    • Diaphorase
    • Dihydrolipoamide dehydrogenase
    • Dihydrolipoyl dehydrogenase
    • Dihydrolipoyl dehydrogenase mitochondrial
    • dld
    • DLDD
    • DLDH
    • DLDH_HUMAN
    • E3
    • E3 branched chain aplha-keto acid
    • E3 component of pyruvate dehydrogenase
    • E3 component of pyruvate dehydrogenase complex 2 oxo glutarate complex branched chain keto acid dehydrogenase complex
    • GCSL
    • Glycine cleavage system L protein
    • Glycine cleavage system protein L
    • LAD
    • lipoamide dehydrogenase
    • Lipoamide reductase
    • Lipoyl dehydrogenase
    • mitochondrial
    • OTTHUMP00000206744
    • OTTHUMP00000206746
    • OTTHUMP00000206748
    • OTTHUMP00000206749
    • PHE 3
    • PHE3
    • Pyruvate dehydrogenase component E3
    see all
  • 機能
    Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes. Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction.
  • 関連疾患
    Note=Defects in DLD are involved in the development of congenital infantile lactic acidosis.
    Defects in DLD are a cause of maple syrup urine disease (MSUD) [MIM:248600]. MSUD is characterized by mental and physical retardation, feeding problems and a maple syrup odor to the urine. The keto acids of the branched-chain amino acids are present in the urine, resulting from a block in oxidative decarboxylation.
  • 配列類似性
    Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  • 翻訳後修飾
    Tyrosine phosphorylated.
  • 細胞内局在
    Mitochondrion matrix.
  • Information by UniProt

画像

  • 15% SDS-PAGE analysis of ab93679 (3µg).

参考文献

ab93679 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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