Recombinant human Leptin protein (ab119739)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      The sequence of the first four N-terminal amino acids was determined and was found to be Ala-Thr-Pro-Val.
    • 分子量
      25 kDa
    • 領域
      428 to 635

特性

Our Abpromise guarantee covers the use of ab119739 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性
    Biological Activity is evidenced by high affinity binding of mammalian leptins at 1:1 molar ratio
  • アプリケーション

    Functional Studies

  • 製品の状態
    Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at -20°C. Store under desiccating conditions.

    Constituent: 0.00004% Sodium bicarbonate

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成
    Centrifuge the vial prior to opening. The lyophilized Leptin Binding Domain is very soluble in water and most aqueous buffers below and above the isoelectric point (~ 5.9). The reconstituted protein should be stored at 4°C. Avoid freeze/thaw cycles.

関連情報

  • 別名
    • FLJ94114
    • LEP
    • LEP_HUMAN
    • LEPD
    • Leptin
    • Leptin (murine obesity homolog)
    • Leptin (obesity homolog, mouse)
    • Leptin Murine Obesity Homolog
    • Leptin Precursor Obesity Factor
    • OB
    • Obese protein
    • Obese, mouse, homolog of
    • Obesity
    • Obesity factor
    • Obesity homolog mouse
    • Obesity Murine Homolog Leptin
    • OBS
    • OTTHUMP00000212285
    see all
  • 機能
    May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
  • 関連疾患
    Defects in LEP may be a cause of obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
  • 配列類似性
    Belongs to the leptin family.
  • 細胞内局在
    Secreted.
  • Information by UniProt

Recombinant human Leptin protein (ab119739) 使用論文

ab119739 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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