製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号O75829
    • 生物種Human
    • 分子量38 kDa

特性

Our Abpromise guarantee covers the use of ab112725 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

  • 製品の状態Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    pH: 6.80
    Constituents: 1.58% Tris HCl, 3.09% DTT, 4% SDS, 0.2% Bromophenol blue, 20% Sucrose

  • 再構成Add 100ul of distilled water.

関連情報

  • 別名
    • BRICD3
    • BRICHOS domain containing 3
    • CH-SP
    • CHM I
    • ChM-I
    • CHM1
    • chondromodulin
    • Chondromodulin I
    • Chondromodulin-1
    • Chondromodulin-I
    • Chondrosurfactant protein
    • LECT 1
    • Lect1
    • LECT1_HUMAN
    • Leukocyte cell derived chemotaxin 1
    • Multiple myeloma tumor suppressor 1
    • MYETS1
    see all
  • 機能Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.
  • 組織特異性Detected in cartilage and cardiac valves (at protein level). Detected in the laminae fibrosa, spongiosa and ventricularis layers of normal cardiac valves (at protein level). Expression is decreased cardiac valves of patients with valvular heart disease (at protein level). Weakly expressed in chondrosarcoma.
  • 配列類似性Belongs to the chondromodulin-1 family.
    Contains 1 BRICHOS domain.
  • 発生段階Expressed at 9 weeks in developing cartilagenous bone rudiments.
  • 翻訳後修飾After cleavage, the post-translationally modified ChM-I is secreted as a glycoprotein.
  • 細胞内局在Endomembrane system and Secreted. Accumulated in the inter-territorial matrix of cartilage.
  • Information by UniProt

Recombinant Human LECT1 protein (ab112725) 使用論文

ab112725 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab112725.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"