Recombinant Human Ku70 + Ku80 protein (ab73790)

製品の概要

  • 製品名Recombinant Human Ku70 + Ku80 protein
  • タンパク質長Protein fragment

法規制情報

製品の詳細

  • 由来Recombinant
  • 由来Baculovirus infected Sf9 cells
  • アミノ酸配列
    • 生物種Human
    • 配列の追加情報KuP70/P80 Human Recombinant produced in SF9 insect cells is a glycosylated, polypeptide chain having a molecular mass of 70,638 Dalton for the p70 subunit and 83,528 Dalton for the p80 subunit.

特性

Our Abpromise guarantee covers the use of ab73790 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    Western blot

  • 精製度> 90 % SDS-PAGE.
    This antibody is expressed with a -6xHis tag and purified by proprietary chromatographic techniques.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 160mM Sodium chloride, 16mM HEPES, pH 8

関連情報

  • 別名
    • CTC75
    • CTC85
    • CTCBF
    • DNA repair protein XRCC5
    • DNA repair protein XRCC6
    • G22P1
    • G22P2
    • KARP1
    • Ku 70
    • Ku 80
    • Ku 86
    • Ku86
    • ML8
    • NFIV
    • TLAA
    • XRCC5
    • XRCC6
    see all
  • 関連性The Ku autoantigen is a heterodimer of 70kDa (p70) and 80kDa (p80) proteins. The p70 / p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. The Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
  • 細胞内局在Nuclear

Recombinant Human Ku70 + Ku80 protein (ab73790) 使用論文

ab73790 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your inquiry. A suitable detection antibody could be against the His tag. For example HRP conjugated: ab1187 ab1269 ab3553 Detection of Ku70/Ku80 heterodimer by Ku antibodies may bear false-negative results since the main reacti...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"