製品の概要

  • 製品名Recombinant Human KRT81 protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号AAH21241
    • 生物種Human
    • 配列MKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC QNSKLEAAVA QSEQQGEAALSDARCKLAELEGALQKA KQDMACLIREYQEVMNSKLGL DIEIATYRRLLEGEEQR LCEGIGAVNVCVSSSRGGVVCGDLCVSGSRP VTGSV CSAPCNGNVAVSTGLCAPCGQLNTTCGGGSCGVGSC GISSL GVGSCGSSCRKC
    • 分子量48 kDa including tags
    • 領域1 to 202
    • タグproprietary tag N-Terminus

関連製品

特性

Our Abpromise guarantee covers the use of ab117016 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    SDS-PAGE

    ELISA

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • 1
    • basic
    • ghHb 1
    • ghHb1
    • ghHkb 1
    • ghHKb1
    • hair
    • Hair keratin K2.9
    • Hard keratin type II 1
    • HB 1
    • HB1
    • hHAKB2 1
    • K2.9
    • K81
    • Keratin
    • Keratin 81
    • Keratin hair basic 1
    • Keratin type II cuticular Hb1
    • Keratin-81
    • Keratin81
    • KRT 81
    • KRT81
    • KRT81_HUMAN
    • KRTHB 1
    • KRTHB1
    • Metastatic lymph node 137 gene protein
    • MLN 137
    • MLN137
    • type II cuticular Hb1
    • Type II hair keratin Hb1
    • Type-II keratin Kb21
    see all
  • 組織特異性Abundantly expressed in the differentiating cortex of growing (anagen) hair. Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla. Expressed in malignant lymph node tissue in breast carcinoma tissue.
  • 関連疾患Defects in KRT81 are a cause of monilethrix (MLTRX) [MIM:158000]. Monilethrix is an autosomal dominant hair disorder characterized clinically by alopecia and follicular papules. Affected hairs have uniform elliptical nodes of normal thickness and intermittent constrictions, internodes at which the hair easily breaks. Usually only the scalp is involved, but in severe forms, the secondary sexual hair, eyebrows, eyelashes, and nails may also be affected.
  • 配列類似性Belongs to the intermediate filament family.
  • Information by UniProt

Recombinant Human KRT81 protein 画像

  • 12.5% SDS-PAGE showing ab117016 at approximately 48.33 kDa.
    Stained with Coomassie Blue.

Recombinant Human KRT81 protein (ab117016) 使用論文

ab117016 has not yet been referenced specifically in any publications.

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