Recombinant Human Kallistatin protein (ab116855)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MHLIDYLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLK IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQ ILEGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLK FLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSE LKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQ EHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSG ITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFN RPFLVVIFSTSTQSVLFLGKVVDPTKP
    • 分子量
      73 kDa including tags
    • 領域
      1 to 427

特性

Our Abpromise guarantee covers the use of ab116855 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 mg/ml. This protein is best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • KAIN_HUMAN
    • KAL
    • Kallikrein binding protein
    • Kallikrein inhibitor
    • Kallistatin
    • KBP
    • KLST
    • KST
    • MGC108582
    • Peptidase inhibitor 4
    • PI-4
    • PI4
    • Protease inhibitor 4
    • Protease inhibitor 4 (kallistatin)
    • Serine (or cysteine) proteinase inhibitor, clade A (alpha 1 antiproteinase, antitrypsin), member 4
    • Serpin A4
    • Serpin peptidase inhibitor clade A member 4
    • Serpin peptidase inhibitor, clade A (alpha 1 antiproteinase, antitrypsin), member 4
    • SERPINA4
    • Tissue kallistatin inhibitor
    see all
  • 機能
    Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.
  • 組織特異性
    Expressed by the liver and secreted in plasma.
  • 配列類似性
    Belongs to the serpin family.
  • 翻訳後修飾
    The N-terminus is blocked.
  • 細胞内局在
    Secreted.
  • Information by UniProt

画像

  • 12.5% SDS-PAGE showing ab116855 at approximately 73.04kDa and stained with Coomassie Blue.

参考文献

ab116855 has not yet been referenced specifically in any publications.

レビューと Q&A

Thank you for contacting us. Here is a protocol that can be applied with this protein (ab116855) to perform an ELISA: 1. Coat antigen (200ng/well) onto the wells in a 96 well mictrotiter plate 2. Block unbound sites with 5% skim milk in PBST 3. A...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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