Recombinant human ITLN1 protein (ab109151)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来CHO cells
  • アミノ酸配列
    • アクセッション番号Q8WWA0
    • 生物種Human
    • 分子量38 kDa including tags
    • 領域17 to 313
    • タグDDDDK tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab109151 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性Enhances glucose transport mediated by insulin.
  • アプリケーション

    Functional Studies

    SDS-PAGE

  • エンドトキシン・レベル< 0.100 Eu/µg
  • 精製度> 95 % SDS-PAGE.

  • 製品の状態Lyophilised
  • 備考After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions. Enhances glucose transport mediated by insulin.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C.

    Preservative: None
    Constituents: PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成Reconstitute with 100µl sterile water to give a final concentration of 0.1mg/ml.

関連情報

  • 別名
    • Endothelial lectin HL 1
    • Endothelial lectin HL-1
    • FLJ20022
    • Galactofuranose binding lectin
    • Galactofuranose-binding lectin
    • hIntL
    • HL 1
    • HL1
    • Intelectin
    • Intelectin 1
    • Intelectin-1
    • Intestinal lactoferrin receptor
    • INTL
    • ITLN
    • ITLN-1
    • ITLN1
    • ITLN1_HUMAN
    • LFR
    • Omentin
    • OTTHUMP00000027882
    see all
  • 機能Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism.
  • 組織特異性Highly expressed in omental adipose tissue where it is found in stromal vascular cells but not in fat cells but is barely detectable in subcutaneous adipose tissue (at protein level). Highly expressed in the small intestine. Also found in the heart, testis, colon, salivary gland, skeletal muscle, pancreas and thyroid and, to a lesser degree, in the uterus, spleen, prostate, lymph node and thymus.
  • 配列類似性Contains 1 fibrinogen C-terminal domain.
  • 発生段階Found in fetal small intestine and thymus.
  • 翻訳後修飾N-glycosylated.
  • 細胞内局在Cell membrane. Secreted. Enriched in lipid rafts.
  • Information by UniProt

Recombinant human ITLN1 protein (ab109151) 使用論文

ab109151 has not yet been referenced specifically in any publications.

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Our products are designed for research purposes and have not been tested for treatment in animal studies. There doesn't appear to be anything in the buffer for this product that would be incompatible with using it...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"