Reconstitute in water to a concentration of 0.1-1.0 mg/ml for extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA)
Chromosome 16 open reading frame 77
Cytokine that promotes the differentiation and viability of monocytes and macrophages. Stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. Ligand for colony-stimulating factor-1 receptor CSF1R.
Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level). Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon.