Recombinant Human Interferon regulatory factor 9 protein (ab126019)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q00978
    • 生物種Human
    • 分子量11 kDa
    • 領域239 to 389

特性

Our Abpromise guarantee covers the use of ab126019 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 製品の状態Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at -20°C.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • 再構成Reconstitute with water to desired concentration.

関連情報

  • 別名
    • IFN alpha responsive transcription factor subunit
    • IFN-alpha-responsive transcription factor subunit
    • Interferon regulatory factor 9
    • interferon stimulated transcription factor 3
    • Interferon-stimulated gene factor 3 gamma
    • interferon-stimulated transcription factor 3, gamma 48kDa
    • IRF 9
    • IRF-9
    • Irf9
    • IRF9_HUMAN
    • ISGF 3 gamma
    • ISGF-3 gamma
    • ISGF3
    • ISGF3 p48 subunit
    • ISGF3G
    • OTTHUMP00000164692
    • OTTHUMP00000164693
    • p48
    • Transcriptional regulator ISGF3 subunit gamma
    see all
  • 機能Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
  • 配列類似性Belongs to the IRF family.
    Contains 1 IRF tryptophan pentad repeat DNA-binding domain.
  • 細胞内局在Cytoplasm. Nucleus. Translocated into the nucleus upon activation by IFN-alpha/beta.
  • Information by UniProt

Recombinant Human Interferon regulatory factor 9 protein (ab126019) 使用論文

ab126019 has not yet been referenced specifically in any publications.

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