Recombinant human Interferon beta protein (Active) (ab71475)
Key features and details
- Expression system: CHO cells
- Purity: >= 95% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies, HPLC
製品の詳細
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製品名
Recombinant human Interferon beta protein (Active)
Interferon beta タンパク質・ペプチド 製品一覧 -
生理活性
Determined by a cytotoxicity assay using human TF-1 cells. The expected ED50 is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
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精製度
>= 95 % SDS-PAGE.
>= 95% HPLC analyses. Due to glycosylation, IFN-ß has an approximate MW of 22.3 kDa based on SDS-PAGE gel -
エンドトキシン・レベル
< 1.000 Eu/µg -
発現系
CHO cells -
アクセッション番号
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タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
配列
MSYNLLGFLQ RSSNFQCQKL LWQLNGRLEY CLKDRMNFDI PEEIKQLQQF QKEDAALTIY EMLQNIFAIF RQDSSSTGWN ETIVENLLAN VYHQINHLKT VLEEKLEKED FTRGKLMSSL HLKRYYGRIL HYLKAKEYSH CAWTIVRVEI LRNFYFINRL TGYLRN -
予測される分子量
20 kDa -
領域
22 to 187 -
配列の追加情報
Full length mature protein, minus the signal peptide.
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関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab71475 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
Functional Studies
HPLC
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製品の状態
Lyophilized -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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再構成For lot specific reconstitution information please contact our Scientific Support Team.
関連情報
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別名
- beta-interferon
- Fibroblast interferon
- IFB
see all -
機能
Has antiviral, antibacterial and anticancer activities. -
配列類似性
Belongs to the alpha/beta interferon family. -
細胞内局在
Secreted. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (3)
ab71475 は 3 報の論文で使用されています。
- Constantin D et al. APOBEC3C, a nucleolar protein induced by genotoxins, is excluded from DNA damage sites. FEBS J 289:808-831 (2022). PubMed: 34528388
- Lyu X et al. Preventing SARS-CoV-2 Infection Using Anti-spike Nanobody-IFN-β Conjugated Exosomes. Pharm Res N/A:1-9 (2022). PubMed: 36163411
- Tsai M et al. The E3 ligase subunit FBXO45 binds the interferon-λ receptor and promotes its degradation during influenza virus infection. J Biol Chem 298:102698 (2022). PubMed: 36379255