Recombinant Human IMPDH2 protein (ab113608)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHHSSGLVPRGSHMADYLISGGTSYVPDDGLTAQQLFNCGDGL TYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAI AMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDV FEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMT KREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKN RDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNS IFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSI CITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALG ASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRY FSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR AMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF
    • 分子量
      58 kDa including tags
    • 領域
      1 to 514
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab113608 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度
    > 90 % SDS-PAGE.
    ab113608 was purified using conventional chromatography.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.03% DTT, 20% Glycerol, 0.88% Sodium chloride

関連情報

  • 別名
    • IMDH2_HUMAN
    • IMP (inosine monophosphate) dehydrogenase 2
    • IMP dehydrogenase 2
    • IMP oxireductase 2
    • IMPD 2
    • IMPD2
    • IMPDH 2
    • IMPDH II
    • IMPDH-II
    • Impdh2
    • Inosine 5' monophosphate dehydrogenase 2
    • Inosine 5' phosphate dehydrogenase 2
    • Inosine monophosphate dehydrogenase type II
    • Inosine-5''-monophosphate dehydrogenase 2
    see all
  • 機能
    Rate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth. It may also have a role in the development of malignancy and the growth progression of some tumors.
  • 組織特異性
    IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.
  • パスウェイ
    Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.
  • 配列類似性
    Belongs to the IMPDH/GMPR family.
    Contains 2 CBS domains.
  • 翻訳後修飾
    The N-terminus is blocked.
  • Information by UniProt

画像

  • 15% SDS-PAGE analysis of ab113608 (3µg)

参考文献

ab113608 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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