Recombinant Human IMPDH2 protein (ab113608)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P12268
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMADYLISGGTSYVPDDGLTAQQLFNCGDGL TYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAI AMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDV FEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMT KREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKN RDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNS IFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSI CITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALG ASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRY FSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR AMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF
    • 分子量58 kDa including tags
    • 領域1 to 514
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab113608 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 90 % SDS-PAGE.
    ab113608 was purified using conventional chromatography.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.03% DTT, 20% Glycerol, 0.88% Sodium chloride

関連情報

  • 別名
    • IMDH2_HUMAN
    • IMP (inosine monophosphate) dehydrogenase 2
    • IMP dehydrogenase 2
    • IMP oxireductase 2
    • IMPD 2
    • IMPD2
    • IMPDH 2
    • IMPDH II
    • IMPDH-II
    • Impdh2
    • Inosine 5' monophosphate dehydrogenase 2
    • Inosine 5' phosphate dehydrogenase 2
    • Inosine monophosphate dehydrogenase type II
    • Inosine-5''-monophosphate dehydrogenase 2
    see all
  • 機能Rate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth. It may also have a role in the development of malignancy and the growth progression of some tumors.
  • 組織特異性IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.
  • パスウェイPurine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.
  • 配列類似性Belongs to the IMPDH/GMPR family.
    Contains 2 CBS domains.
  • 翻訳後修飾The N-terminus is blocked.
  • Information by UniProt

Recombinant Human IMPDH2 protein 画像

  • 15% SDS-PAGE analysis of ab113608 (3µg)

Recombinant Human IMPDH2 protein (ab113608) 使用論文

ab113608 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab113608.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"