Recombinant Human IL3RB protein (Fc Chimera) (ab83919)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来HEK 293 cells
  • アミノ酸配列
    • アクセッション番号P32927
    • 生物種Human
    • 配列Theoretical Sequence: WERSLAGAEETIPLQTLRCYNDYTSHITCRWADTQDAQRLVNVTLIRRVN EDLLEPVSCDLSDDMPWSACPHPRCVPRRCVIPCQSFVVTDVDYFSFQPD RPLGTRLTVTLTQHVQPPEPRDLQISTDQDHFLLTWSVALGSPQSHWLSP GDLEFEVVYKRLQDSWEDAAILLSNTSQATLGPEHLMPSSTYVARVRTRL APGSRLSGRPSKWSPEVCWDSQPGDEAQPQNLECFFDGAAVLSCSWEVRK EVASSVSFGLFYKPSPDAGEEECSPVLREGLGSLHTRHHCQIPVPDPATH GQYIVSVQPRRAEKHIKSSVNIQMAPPSLNVTKDGDSYSLRWETMKMRYE HIDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRVRT SRTGYNGIWSEWSEARSWDTESVLPMWGSSNTKVDKKVEPKSCDKTHTCP PCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNW YVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKA LPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDI AVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSV MHEALHNHYTQKSLSLSPGK
    • 領域1 to 443
    • 配列の追加情報Fused with the Fc region of Human IgG1 at the C-terminus.

特性

Our Abpromise guarantee covers the use of ab83919 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 95 % SDS-PAGE.

  • 製品の状態Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Trehalose, 1% Human serum albumin, PBS

  • 再構成It is recommended that 0.5 ml of sterile phosphate-buffered saline be added to the vial. Following reconstitution short-term storage at 4°C is recommended, with longer-term storage in aliquots at -18 to -20°C. Repeated freeze thawing is not recommended.

関連情報

  • 別名
    • /granulocyte-macrophage colony-stimulating factor receptor, beta
    • Beta-C
    • CD131
    • CDw131
    • Colony stimulating factor 2 receptor beta
    • Colony stimulating factor 2 receptor beta low affinity (granulocyte macrophage)
    • Common beta chain
    • Csf2rb
    • Cytokine receptor common beta chain
    • Cytokine receptor common beta chain precursor (CDw131 antigen)
    • Cytokine receptor common subunit beta
    • GM CSF/IL 3/IL 5 receptor common beta chain
    • GM-CSF/IL-3/IL-5 receptor common beta subunit
    • IL3RB
    • IL3RB_HUMAN
    • IL5RB
    • Interleukin 3 receptor, beta
    • Interleukin 3 receptor/granulocyte macrophage colony stimulating factor 3 receptor beta (high affinity)
    • Interleukin 5 receptor, beta
    • SMDP5
    • stimulating factor 3 receptor, beta (high affinity)
    see all
  • 機能High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.
  • 配列類似性Belongs to the type I cytokine receptor family. Type 4 subfamily.
    Contains 2 fibronectin type-III domains.
  • ドメインThe WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is required for JAK interaction and/or activation.
  • 細胞内局在Membrane.
  • Information by UniProt

Recombinant Human IL3RB protein (Fc Chimera) 画像

  • Densitometry of protein isoforms visualised by 2-DE.
    The densitometry scan demonstrates the purified Human cell expressed protein exists in multiple isoforms, which differ according to their level of post-translational modification.
    The triangle indicates the theoretical MW and pI of the protein.
  • 1D SDS-PAGE of ab83919 before and after treatment with glycosidases to remove oligosaccharides.
    Lane 1: ab83919
    Lane 2: ab83919 treated with PNGase F to remove potential N-linked glycans
    Lane 3: ab83919 treated with a glycosidase cocktail to remove potential N- and O-linked glycans.
    Approximately 5 μg of protein was loaded per lane; Gel was stained using Deep Purple™.

Recombinant Human IL3RB protein (Fc Chimera) (ab83919) 使用論文

ab83919 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab83919.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"