由来 Escherichia coli
配列 MRPSGRKSSK MQAFRIWDVN QKTFYLRNNQ LVAGYLQGPN VNLEEKIDVV PIEPHALFLG IHGGKMCLSC VKSGDETRLQ LEAVNITDLS ENRKQDKRFA FIRSDSGPTT SFESAACPGW FLCTAMEADQ PVSLTNMPDE GVMVTKFYFQ EDE
領域 24 to 177 特性
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
エンドトキシン・レベル < 0.100 Eu/µg
精製度 > 95
% SDS-PAGE. ab50081 purity was assessed also by HPLC.
Endotoxin level is less than 0.1 ng per µg (1EU/µg).
This protein is the 17.2 kDa secreted isoform of IL1RA.
Concentration information loading... 前処理および保存
Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.
Constituents: 5mM Tris, 25mM Sodium chloride, pH 8
再構成 Reconstitute to 1mg/ml with distilled water.
機能 Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.
組織特異性 The intracellular form of IL1RN is predominantly expressed in epithelial cells.
関連疾患 Microvascular complications of diabetes 4 Interleukin 1 receptor antagonist deficiency
細胞内局在 Cytoplasm and Secreted.
Information by UniProt
Recombinant Human IL1RA protein 画像
Anti-IL1RA antibody ( ab2573) at 1 µg/ml + Recombinant Human IL1RA protein (ab50081) at 0.01 µg Secondary Goat Anti-Rabbit IgG H&L (HRP) preadsorbed ( ab97080) at 1/5000 dilution developed using the ECL technique Performed under reducing conditions. Exposure time : 20 seconds
Recombinant Human IL1RA protein (ab50081) 使用論文
has not yet been referenced specifically in any publications.
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