Recombinant human IL-17 (IL-17A) protein (ab9567)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
製品の詳細
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製品名
Recombinant human IL-17 (IL-17A) protein
IL-17A タンパク質・ペプチド 製品一覧 -
生理活性
Assay #1: Measured by its ability to induce IL-6 production by NHDF cells, using a concentration range of 0.5-1.5 ng/ml.
Assay #2: Measured by its ability to induce GROα production by HT-29 cells, using a concentration range of 0.5-5.0 ng/ml. -
精製度
> 98 % SDS-PAGE.
Sterile filtered Greater than 98% by SDS-PAGE gel and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg). -
エンドトキシン・レベル
< 1.000 Eu/µg -
発現系
Escherichia coli -
アクセッション番号
-
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
配列
MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA -
予測される分子量
17 kDa -
領域
20 to 155
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製品の詳細
Recombinant human IL-17A protein
関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab9567 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Functional Studies
SDS-PAGE
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製品の状態
Lyophilized -
備考
Measured by its ability to induce IL6 production by NHDF cells, using a concentration range of 0.5-1.5 ng/ml.
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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再構成Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex.
関連情報
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別名
- CTLA 8
- CTLA-8
- CTLA8
see all -
機能
Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts. -
組織特異性
Restricted to activated memory T-cells. -
配列類似性
Belongs to the IL-17 family. -
翻訳後修飾
Found both in glycosylated and nonglycosylated forms. -
細胞内局在
Secreted. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (3)
ab9567 は 3 報の論文で使用されています。
- Wang W et al. Astilbin reduces ROS accumulation and VEGF expression through Nrf2 in psoriasis-like skin disease. Biol Res 52:49 (2019). PubMed: 31492195
- Wang Z et al. Role of miR-106-mediated mitogen-activated protein kinase signaling pathway in oxidative stress injury and inflammatory infiltration in the liver of the mouse with gestational hypertension. J Cell Biochem N/A:N/A (2019). PubMed: 31773798
- Lv Q et al. Interleukin-17A and heparanase promote angiogenesis and cell proliferation and invasion in cervical cancer. Int J Oncol 53:1809-1817 (2018). PubMed: 30066843